These are naturally occurring neurotransmitters, peptides, that function as the body’s endogenous opioids. Released primarily by the pituitary gland and central nervous system, they serve to modulate pain perception. A classic example is the “runner’s high,” a state of euphoria experienced after sustained physical exertion, resulting from the release of these substances.
Their significance lies in their role in stress reduction, mood elevation, and pain management. Understanding these substances is crucial in psychological studies examining the biological underpinnings of emotions, motivation, and behavior. Historically, research into these naturally produced pain relievers has spurred development in pharmacological interventions for managing discomfort and improving mental well-being.